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Diverticulitis Club > Blog > Causes > What Causes Diverticular Disease?
Causes

What Causes Diverticular Disease?

Last updated: April 17, 2026 11:33 am
Last updated: April 17, 2026
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What Causes Diverticular Disease?
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  • Can Medications Cause Diverticular Disease?
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What Causes Diverticular Disease?

The exact cause of diverticular disease is unknown, but it is thought to be due to a combination of factors, including: diet, age, smoking, obesity, inactivity and some medications.

Diverticular disease refers to the presence of small, bulging pouches called diverticula that can form in the lining of the colon. The exact cause of diverticular disease is not fully understood, but several factors may contribute to its development.

     

      • Age: The risk of developing diverticular disease increases with age. It is more commonly observed in individuals over the age of 40 and becomes more prevalent as people get older.

      • Low-fiber diet: A diet low in fiber is believed to play a significant role in the development of diverticular disease. When the diet lacks adequate fiber, the stools become harder and more difficult to pass, exerting increased pressure on the colon walls. Over time, this increased pressure can lead to the formation of diverticula.

      • Lack of physical activity: Sedentary lifestyles and a lack of regular physical activity have been associated with an increased risk of diverticular disease. Exercise and physical activity help maintain bowel regularity and promote healthy digestion.

    It is estimated that about 1 in 5 people over the age of 40 have diverticula, and about 1 in 10 people with diverticula will develop diverticulitis at some point in their lives

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        • Genetics: There is evidence suggesting a genetic component to diverticular disease. Individuals with a family history of the condition may have a higher risk of developing it themselves.

        • Obesity: Being overweight or obese has been linked to an increased risk of developing diverticular disease. Excess weight can contribute to increased pressure on the colon walls, potentially leading to the formation of diverticula.

        • Smoking: Smoking has been identified as a potential risk factor for diverticular disease. It is believed that smoking may contribute to inflammation and weaken the colon wall, making it more susceptible to diverticula formation.

      More Reading

      What Causes Diverticular Disease?


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      Can Medications Cause Diverticular Disease?

      Certain medications: Some medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs), may increase the risk of diverticular disease.

      It’s important to note that while these factors are associated with diverticular disease, not everyone with these risk factors will develop the condition. Additionally, diverticular disease may have a complex and multifactorial etiology, and further research is needed to fully understand its causes.

      Diverticular disease can be a chronic condition, but it can be managed with lifestyle changes and medication. If you have any concerns about diverticular disease, talk to your doctor.

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      ByMark
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      After being diagnosed with diverticulitis over 10 years ago, I wanted to understand more about this disease from the people who live with it. Diverticulitis Club was created to provide member led coping strategies and allow connections with other real-world sufferers

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